I printed this model on my Anycubic Kobra 2 in white PLA with 0.2mm layer height without supports, 3 walls and 7% adaptive cubic infill. Scaled it to 130% which was the largest I could fit on my bed (220x220), it took 8 hours to print.
I had some issues with curved overhangs (especially around the cheek bones) but otherwise it printed in pretty decent quality, not the best but acceptable I would say. I would probably add organic supports for the cheekbones if I print another.
Mostly purge and to make sure the bed is level. I don’t bother with it personally. I will use a brim on occasion is i’m printing something significantly taller than it is wide
I find skirts useful to make sure I’ve got consistent flow before it starts printing the object.
This way there isn’t oozing or a delay from a previous retraction. A good purge, as you say, to get primed and ready to go.