Lawrence Faucette, the second living person to receive a genetically modified pig heart in a transplant, has died six weeks after the experimental procedure. The University of Maryland Medical Center, where the experimental procedure had been performed, said the heart began to show signs of rejection in recent days.
“Mr. Faucette’s last wish was for us to make the most of what we have learned from our experience, so others may be guaranteed a chance for a new heart when a human organ is unavailable. He then told the team of doctors and nurses who gathered around him that he loved us. We will miss him tremendously,” Dr. Bartley Griffith, clinical director of the Cardiac Xenotransplantation Program at the University of Maryland School of Medicine, said in a statement. Griffith had performed the experimental surgery.
My dad had a double lung transplant several months ago…we were told by his transplant team that, with transplants, rejection is a “when”, not an “if”. However, if caught early enough, the docs can do an incredible amount to combat rejection.
Complete layperson here but it kind of astounds me that we haven’t cracked the code for this friend-or-foe identification. One would think there is some identifier or expression that is evaluated by the immune system and if we could match that we’d be golden but clearly not that simple.
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Cue The Island, lol
Taking immunology right now, it’s incredibly complicated. Immune cells aren’t like any other cells in our bodies, they’re absolutely bonkers.
We can’t even cure autoimmune diseases yet. Why the fuck has my immune system decided my own tissues are the enemy?! Such a dick move.
Fucking confused white blood cells need to figure out their shit
Fair enough.
These are very complicated processes that are difficult to interpret with such a (relatively) small number of people looking at it.
I started reading the book Immune by the team that runs the Kurzgesagt (In a Nutshell) YouTube channel. The book is written for laypeople like us to understand, but I didn’t get very far before going “holy shit this is ridiculously complicated”. Honestly, just the fact that scientists understand any of this astounds me.
Rheumatologists are practicing alchemy, I’m convinced.
Honestly, this might sound weird, but if my body ever got to that point, I’d rather just go die in a war.
Better to go out with a bang than a wimper, imo.